We explore the molecular
processes of life


2017 Pilot Project Program — Letters of Intent (LOI) Now Being Accepted


 BioMT requests proposals for pilot projects relating to its theme: identification, validation, or development of molecular targets associated with human disease.

For more information, including LOI instructions, see:  BioMT Pilot Project LOI (pdf)


What we do

Biology: We explore the operation and control phosphorylation and protein-protein interaction networks, conformational switches, microRNA regulatory pathways, and intracellular trafficking and degradation machineries.

Mentoring: We accelerate the research and career trajectories of students, post-docs, and junior faculty members. 

Targets: We seek new therapeutic targets for brain cancer, colon cancer, pancreatic cancer, airway infection, and inflammation.

Tools: We integrate insights from protein biochemistry and engineering, biophysics, high-resolution microscopy, and chemical, structural and computational biology.


Who we are

60 scientists

15 labs

10 departments

3 schools

We are looking to grow! Our labs welcome students through the MCB, PEMM, QBS, Chemistry, and Computer Science graduate programs. We welcome applications from outstanding post-doctoral fellows on an on-going basis. We are also partnering across campus to launch a series of faculty searches over the next five years.


Applications are now being accepted for the following positions:

Research Scientist in Protein Biochemistry

Research Scientist in Cellular and Molecular Imaging




Our history

The institute is a faculty-led initiative developed over the past several years. We set out to exploit synergies between the curiosity-based investigation of fundamental biological mechanisms and the early-stage identification and validation of molecular therapeutic targets. Our goal is to leverage the strengths of our intensive and collaborative research environment.

The institute was launched in May 2016 as an NIH Center of Biomedical Research Excellence, with a $12.5M award from the NIH and strong institutional support from Dartmouth College. In addition to funding for four junior faculty research projects, BioMT also supports advanced scientific resources for cross-campus use, faculty and student mentoring, an annual symposium, and a weekly seminar series. 


Our Partners

Funding is provided by award P20-GM113132 from the IDeA program of the NIH National Institute of General Medical Sciences, Dartmouth College, the Geisel School of Medicine, the Thayer School of Engineering, and the Norris Cotton Cancer Center

We also work closely with the Digital Arts, Leadership & Innovation (DALI) Lab, the Dartmouth Entrepreneurial Network (DEN), other IDeA Programs at Dartmouth (immunology, Lung Biology, Molecular Epidemiology, and Quantitative Biology COBRE programs and NH-INBRE) and across New England (Vermont Genetics Network and Maine INBRE).