Research Project 2

Identifying Mitophagy Receptors as Targets in Ras-dysregulated Cells

Michael Ragusa, PhD

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal and challenging cancers to treat in the United States. The growth of PDAC tumors is dependent on a cellular degradation process, termed autophagy. We are combining biochemical and cellular approaches to uncover the role of autophagy in PDAC.

Saccharomyces cerevisiae were stained with MitoTracker Red CMXRos and imaged using a Zeiss LSM 880 with Airyscan to monitor mitochondrial dynamics.

Saccharomyces cerevisiae were stained with MitoTracker Red CMXRos and imaged using a Zeiss LSM 880 with Airyscan to monitor mitochondrial dynamics.